Monday, February 11, 2019

Basic components of the immune system part 4




Up to the 1940s the general dogma held that only antibodies were involved in the immune response. Dr Merril Chase, who began his experiments in a laboratory devoted primarily to the humoral response, clearly showed in a series of elegant experiments that immunity was not just humoral but that a cellular response by the lymphocytes could also produce immunity. Some of the best examples of the power of cellular immunity may be found in the many experiments in which transfer of cells can induce autoimmune disease in animals and humans as well as rejection of an organ graft in both  animals and humans by cells.

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