However, the female-to-male ratio varies widely among different diseases, being as high as 9:1 in SLE, Sjogren's syndrome and autoimmune thyroiditis and as low as 1:1 in TID , Goodpasture's syndrome and vitiligo.. The mean age of onset also varies widely, with some disorders typically occurring early in childhood (eg TID, juvenile rheumatoid arthritis), others in childbearing years (age 15-45, eg SLE), and still others in later life (eg Sjogren's syndrome).
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