In fact, a significant obstacle in HIV vaccine research has been the difficulty in developing an appropriate animal model with many of the features of human HIV infection. The only animals susceptible to experimental infections with HIV are chimpanzees, Pantroglodytes, and pigtail macaques, Macaca nemestrina. These animals maintain low levels of persistent virus but do not develop clinical manifestations of AIDS. In contrast, Asian monkeys, especially rhesus monkeys from India, are highly susceptible to SIVmac infection and progressively develop an immunodeficiency syndrome that is similar to human AIDS. Plasma viral levels during acute and chronic SIVmac251 infection in these animals parallel those observed in humans, with some animals containing virus spontaneously and progressing to disease slowly as in HIV-1 infected human long-term nonprogressors. In contrast, others maintain high viral loads and behave like human rapid progresses. As in HIV-1 infected humans, the cellular immune response to SIVmac during acute and chronic disease differs significantly, and evidence of immune escape has been well documented. This is particularly true of the mucosal immune system, especially the many CD4 CCR5 T cells in the gut associated lymphoid tissue, the major site of the viral replications and of CD4 T-cell depletion in SIV-infected macaques. This also mimics the human diasease and thus the SIV macaque model is currently considered the most appropriate animal model for studies on potential protective immune responses against HIV.
Study MBBS in Philippines has one of the best education systems in Asia. It is one of the best place for Indian students to study completely in English, at affordable prices and high quality Medical Education.
ReplyDeleteEmilio Aguinaldo College Of Medicine is best medical college in Philippines.
Best Option to Study mbbs in EAC for Indian Students
Emilio Aguinaldo College (EAC) was founded in 1951 under the name of Marian School of Midwifery. The Emilio Aguinaldo College of Medicine was established on July 23, 2001, and it has two campuses in Manila city and greater Manila. It is approved by Commission of Higher Education (CHED) Philippines.
University of Perpetual Help System Dalta Top Medical College in Philippines
University of Perpetual Help System Dalta (UPHSD), is a co-education Institution of higher learning located in Las Pinas City, Metro Manila, Philippines. founded in 1975 by Dr. (Brigadier) Antonio Tamayo, Dr. Daisy Tamayo, and Ernesto Crisostomo as Perpetual Help College of Rizal (PHCR). Las Pinas near Metro Manila is the main campus. It has nine campuses offering over 70 courses in 20 colleges.
The Davao Medical School Foundation, Inc. (DMSFI) was established in July 1976 in response to the recognition of the lack of doctors serving rural communities and lack of specialist in urban centres of Mindanao. Its College of Medicine was thus the first such college to be set up in Mindanao and is dedicated to providing medical education and training of the highest order, leading to the provision of effective medical care in both rural and urban communities.
UV Gullas College of Medicine is one of Top Medical College in Philippines in Cebu city. International students have the oppertunity to study medicine in phillipines at affordable cost and world class University. The college has successful alumni who have achieved well in the fields of law, business, politics, academe, medicine, sports and other endeavors. At University of the Visayas, we prepare students for a global competition.