Wednesday, December 12, 2018
Pediatric kidney transplantation part 85
Cytomegalovirus (CMV)
Cytomegalovirus is another member of the herpes virus family. Like HSV, and Epstein Barr virus, it is very common, between 50% and 90% of adults have been infected with CMV. Your child will be tested prior to transplant to determine if they have antibodies against CMV.
Due to the effects of your child's immunosuppression medications, CMV is an important cause of disease after kidney transplant. CMV that is already present in your child (without any symptoms) may become active or CMV may be passed to your child as anew infection through the transplanted kidney or in other ways.
Most often CMV infection cause no symptoms in healthy children and adults. However, even when there are no symptoms, CMV stays in the body lifelong and on occasion can shed in secretions such as saliva, urine, semen or vaginal secretion.
CMV infection after transplant may cause no symptoms or there can be a wide range of symptoms, including fever, join pain, reduce white blood cell count, pnemonia or gastritis (severe stomach upset). Because the wide variety 0f symptoms, this virus must be considered as unexplained infection in someone who receives a transplant.
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