A dialysis extraporeal circuit (containing blood lines and a dialyser) contains between 200-300mls. This blood filled circuit can clot at any stage resulting in blood loss to the patient.
Measures to minimise the risk of clotting within the circuit include:
Ensuring adequate anticoagulation is used
Maintaing optimal blood flow
Removing fluid within the patients safe/tolerated limits (no more than 5% of body weight or 10-15 mls/kg/hour)
Ensuring that the dialysis machine tests are complete and passed, indicating the machine is safe to use
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