Lectin pathway
The third pathway of complement activation is created by the mannose-binding lectin (MBL), a circulating protein that binds to carbohydrate on the surface of many microorganisms. MBL (structurally related to C1q) activates complement through a serine protease known as MBL-associated serine protease. Deficiency in circulating levels of MBL are associated with frequent infections in childhood.
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