IFN-γ is a potential activator of macrophages and is most often used in conditions in which defective macrophage function occurs. Examples of these disorders are lepromatous leprosy, leishmaniasis and chronic granulomatous disease. IFN-γ works by increasing phagocytic bactericidal activity, but only some patients show enhanced superoxide activity, implying that IFN-γ works by several different mechanisms.
No comments:
Post a Comment