The T cell receptor complex recognizes small peptides presented to it by the major histocompatibility complex class I and II and depends on the type of T cell. Helper T cells (CD4) recognize class II antigens while suppressor cytotoxic T cells (CD8) recognize class I antigens.Because of the rather low affinity of the reactions, recognition of processed antigen alone is not sufficient to activate T cells. Soluble interleukins are needed to complete the picture and are generated during the antigen processing.
No comments:
Post a Comment