Available prediction tools like the Immune Epitope Data Base and Analysis Resource could be used to facilitate this enterprise by experienced labs. Furthermore, HLA matching at the T cell epitope or cryoptotope level would be also expected to be affected by recipient's polymorphic profile in molecules involved in antigenic peptide generation and perhaps by the T cell receptor repertoire of each recipients (shaped according to their own HLA alleles). It might or not be the right "match" from the HLA match maker but could provide a fair "deal" in the assessment of compatibility between the donor and the recipient (potentially a new tool dubbed as HLA match dealer)
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